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Jama 2005; 293 16171625 kranzler hr, wesson dr, billot l drug abuse sciences naltrexone depot study group ; naltrexone depot for treatment of alcohol dependence a multicenter, randomized, placebo-controlled clinical trial.

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2005; 115 10 ; 2762-277 rubio g, ponce g, rodriguez-jimenez r, jimenez-arriero ma, hoenicka j, palomo clinical predictors of response to naltrexone in alcoholic patients who benefits most from treatment with naltrexone and narcan.

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after naltrexone treatment is discontinued, the patients should be alerted that they may be more sensitive to opioids, even at lower doses.

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in fact, one multisite study showed that naltrexone-taking subjects who attended mutual-support groups, such as aa, had better outcomes.

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